Indocyanine green kinetics to assess liver function: Ready for a clinical dynamic assessment in major liver surgery?

Using indocyanine green test to avoid post-hepatectomy liver dysfunction.

BACKGROUND Post-operative hepatic failure is the most important concern for hepatocellular carcinoma (HCC) patients undergoing hepatectomy. The aim of this study was to determine the safe line of hepatectomy to prevent liver failure. METHOD Clinical profiles of 117 patients with HCC who underwent hepatectomies in Chang Gung Memorial Hospital from Jan. 2002 through Jun. 2003 were reviewed. Pat...

Use of Liver Stiffness Measurement for Liver Resection Surgery: Correlation with Indocyanine Green Clearance Testing and Post-Operative Outcome

BACKGROUND Liver stiffness measurement (LSM) using transient elastography has recently become available for the assessment of liver fibrosis. Whether LSM can predict the functional liver reserve in patients undergoing liver resection is not certain. AIM To correlate liver stiffness measurement (LSM) with indocyanine green (ICG) clearance test and liver biochemistry, and to determine its usefu...

Indocyanine green elimination test in orthotopic liver recipients.

OBJECTIVE To determine its predictive capability on graft quality and resultant clinical outcome, the indocyanine green (ICG) elimination test was performed by a spectrophotometric method and a noninvasive finger-piece method with 50 orthotopic liver transplantations. BACKGROUND Early detection of poor-functioning hepatic grafts is one of the most important issues in liver transplantation, bu...

Intraoperative functional liver remnant assessment with indocyanine green clearance: another toehold for climbing the “ALPPS”.

Methodology to Assess Clinical Liver Safety Data

Analysis of liver safety data has to be multivariate by nature and needs to take into account time dependency of observations. Current standard tools for liver safety assessment such as summary tables, individual data listings, and narratives address these requirements to a limited extent only. Using graphics in the context of a systematic workflow including predefined graph templates is a valu...